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Description
Effects of weight reduction on blood lipids and lipoproteins: A meta-analysis

Long-chain fatty acids (LCFAs) cannot directly cross the mitochondrial membrane because of their high polarity and are activated to long-chain acyl-CoA by acyl-CoA synthetase (ACS)
important etiological factors and management

This is further supported by improved outcomes in the matched cohort comparisons within the study group relative to the control group

L-carnitine (LC) is a natural endogenous cofactor for the translocation of long-chain fatty acids from the cytoplasmic compartment into the mitochondria, where beta-oxidation enzymes are located (3)