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Description
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Severe Kidney Disease: Carnitine is processed by the kidneys, and in individuals with severe kidney disease, it can accumulate in the body, potentially leading to toxicity
Important to note is that there is no anaerobic reserve for residual energy production from FA metabolism
Severe adverse reactions are rare but may include anaphylaxis or exacerbation of preexisting conditions
The carnitine molecule formed is then shuttled back into the intermembrane space by the same cotransporter (CACT) while the fatty acyl-CoA enters -oxidation
