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Lifestyle medicine and related non-pharmacological interventions have also attracted attention, including nutritional optimization (Mohamed et al., 2023), appropriate physical activity (Zalewski et al., 2019), and stress management (Lopez et al., 2011)

Studies show that NNMT inhibition influences metabolic pathways associated with healthspan and longevity

Fourth, the cross-sectional design and cardiac-focused approach limit assessment of temporal dynamics and systemic inter-organ responses

Ahmadian, E., Eftekhari, A., Samiei, M., Maleki Dizaj, S