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Remarkably, mice overexpressing CCK in the mPFC exhibited exacerbated anxiety-like behavior, as indicated by a significant decrease in both time spent and number of entries into the open arms of the elevated plus maze after SDS (Fig

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We also compared the metabolic and phenotypic consequences of genetically impairing 2-OG or glutarate metabolism, and depleted HeLa cells of ABHD11 or GCDH (Fig

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van der Merwe & Bloomer, 2016 In cellular studies, MSM was shown to inhibit nuclear factor-kappa B (NF-B), a key driver of chronic inflammation and immune dysregulation in autoimmune diseases
