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Primary carnitine deficiency is a genetic disorder of the cellular carnitine-transporter system that typically appears by the age of five with symptoms of cardiomyopathy, skeletal-muscle weakness, and hypoglycemia

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This transporter exhibits high affinity for ALCAR, enabling efficient delivery to neuronal cells

(2015) Nutrition | Velasquez, M., Ramezani, A., Manal, A., et al: Trimethylamine N-Oxide: The Good, the Bad and the Unknown