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These studies have identified specific biomarkers of oxidative damage, elucidated the dysregulation of antioxidant defense systems, mapped connections between oxidative stress and inflammatory pathways, and began to explore the influence of CFTR genotype and modulator therapies on the redox landscape of CF

Animal studies show that SAM-e stimulates the production of cartilage, which is critical in reversing the disease process

Marracci GH, Jones RE, McKeon GP, Bourdette DN

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