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[DOI] [PubMed] [Google Scholar] 100.Ueno Y, Koike M, Shimada Y, Shimura H, Hira K, Tanaka R, et al

Next, serine hydroxymethyltransferase cleaves -hydroxy-- N -trimethyllysine into - N -trimethylaminobutyraldehyde and glycine, using pyridoxal 5-phosphate as a cofactor

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Neuroinflammation is primarily caused by astrocyte and microglial activation and proliferation, activation, and translocation of transcription factors such as NF-B, and increased production of cytotoxic cytokines such as TNF- and IL-1 (Afshin-Majd et al