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Collectively, these results indicate that through the elimination of oxidative stress, extracellular signalregulated kinase activation, and ER stress, l-Carnitine reduced cell autophagy/apoptosis and concomitantly increased cell viability in RTCs

however, it also involves sensors at the cellular and organelle level in the liver, pancreas, muscles, adipose tissues, and gut [30,31]

When the carotid artery and cerebral cortex of subjects within the control group were inspected, a high level of autophagy markers, light chain 3 (LC-3) and Beclin-1 (BECN-1), and apoptosis was found within the carotids as well as endothelial, vascular and cerebral cortex evidenced by a significant rise in caspase-3 expression and reduced Bcl-2 mRNA gene expression

Cure of alzheimers dementia requires addressing all of the affected brain cell types
