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Because cuproptosis preferentially targets cells with high oxidative phosphorylation (OXPHOS) dependency, whereas glycolytic tumors remain relatively resistant, it exposes a distinct metabolic vulnerability in cancer and presents unique therapeutic opportunities 165,166

Dai S, Hirayama T, Abbas S, Abu-Amer Y

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AAV2-GAD gene therapy for advanced Parkinson's disease: a double-blind, sham-surgery controlled, randomised trial

Takeaway While more research is needed, LDN shows promise in mental health due to its effects on endorphins, neuroinflammation, and opioid system modulation