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Description
In some embodiments, the presently disclosed subject matter provides a method for treating a disorder, disease, or condition associated with oxidative stress in a subject in need of treatment thereof, the method comprising administering to the subject a therapeutically effective amount of a compound of formula (I) or a pharmaceutical composition thereof

1A ) to the apoplast, we added suitable signal peptides for targeting to the secretory pathway to the N-terminus of existing roGFP2-Orp1 constructs (Nietzel et al ., 2019)

Hewson CA, Patel S, Calzetta L, Campwala H, Havard S, Luscombe E, et al

10.1016/j.injury.2017.11.032 64 PufeT.Scholz-AhrensK

Intriguingly, we observed that the anti-ferroptosis effect of selenomethionine was independent of SCLY (Fig
