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These results also help explain the relatively low toxicity of ICA-1s on normal tissue
3-Methylglutaconyl-CoA hydratase (encoded by the AUH gene) then converts itaconyl-CoA to citramalyl-CoA
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Special nuclear receptors are used as sensors for metabolites such as hormones, vitamins, and lipids
All cited studies are conducted in rodent or in-vitro systems consistent with the molecule's RUO classification
