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This aligns with the fact that overexpression of PPAR coactivator 1-alpha (PGC-1), a regulator of mitochondrial biogenesis, increases the generation of CD8 central memory T cells and, in general, improves murine immune responses following infection, immunization, and in the generation of antitumor immunity (131)

More interestingly, exogenous copper can promote ferroptotic cell death, but not Cuproptosis, by directly binding to GPX4 and further increasing GPX4 degradation [176]

Based on the pathogenesis of blue light damage, anti blue light damage drugs can include free radical scavengers, antioxidants, anti-inflammatory drugs, and gene therapy (Pan et al., 2023)

NAD(P)H: Quinone oxidoreductase 1, glutathione S-transferase M1, environmental tobacco smoke exposure, and childhood asthma

Oxidative modification of lens crystallins by H 2 O 2 and chelated iron
