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Conversely, North Africa and the Middle East, Caribbean, and Southeast Asia exhibited the highest ASIR, indicating particularly high disease burden in North Africa and the Middle East

This study identified ER as the major target for QIs-induced perturbations and a significant protective role of GSTP1 by alleviating loss of cell viability, enhancing detoxification of reactive QIs, and attenuating apoptosis

doi: 10.1155/2019/5028181

Under such circumstances, the supplementation with either organic or inorganic forms of selenium is a widely adopted approach to guarantee sufficient selenium levels