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The aim to improve the effect of metformin led to the development of phenformin 43 , which showed an improved cellular uptake compared to metformin 44

226 Other Medical Treatments Drugs that help strengthen the bladder neck muscle by activating the sympathetic nervous system may be helpful in treating some cases of retrograde ejaculation and anejaculation

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The integration of advanced technologies such as wearable devices (for continuous passive data collection), at-home testing kits (for convenience), and high-throughput profiling now enables repeated, real-time measurements and standardised dynamic data collection, which were not previously accessible or widely utilised