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An unbiased metabolic screening using liquid chromatography-tandem mass spectrometry identified TMAO, as a key gut microbiome-derived metabolite that enhances antitumor immunity in pancreatic ductal adenocarcinoma (PDAC) (238)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 143.Atay S., Godwin A.K

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Cancer 21 , 903914 (2014)

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'Arrested Development' Figured Out How to Make It Hilarious"

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This is consistent with the original description of the Johnsen scoring system, which emphasizes germ cell maturation rather than morphometric parameters 31

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