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None of the guidelines reported using systematic literature search methods to inform recommendations relevant to this Rapid Review, which limits the quality of these guidelines, and some of the recommendations were based on evidence that was of low or moderate quality, or not assessed for quality, which reduces the certainty of the recommendations summarized in this report

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Torres NV, Rodrguez F, Gonzlez-Alcn C, Voit EO: An indirect optimization method for biochemical systems: Description of the method and application to ethanol, glycerol and carbohydrates production in Saccharomyces cerevisiae

Oxygen radicals shaping evolution: why fatty acid catabolism leads to peroxisomes while neurons do without it: FADH 2 /NADH flux ratios determining mitochondrial radical formation were crucial for the eukaryotic invention of peroxisomes and catabolic tissue differentiation

El estudio cumple con las normas establecidas por los correspondientes comits de tica de la Universidad de Caldas