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Joint pain developing after starting B12 may reflect: Pre-existing musculoskeletal conditions becoming more noticeable Concurrent inflammatory or degenerative joint disease Reactions to excipients in certain formulations The natural course of an underlying condition If you experience persistent or worsening joint symptoms after beginning B12 supplementation, it is advisable to consult your GP or healthcare provider

Other suitable treatments must accompany PRP injections to eradicate the problem from its roots and provide long-term relief

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[Google Scholar] Engel-Yeger B, Muzio C, Rinosi G, et al