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Reduced glutathione acts as an endogenous antioxidant in different cell types ( Reference Pompella, Visvikis and Paolicchi 19 ) and deactivates reactive oxygen species

The biophysics of superoxide dismutase-1 and amyotrophic lateral sclerosis

doi: 10.3389/fcell.2024.1435125 Received 19 May 2024 Accepted 27 June 2024 Published 11 July 2024 Volume 12 - 2024 Edited by Takehito Ouchi, Tokyo Dental College, Japan Reviewed by Kui Xu, Anhui University of Chinese Medicine, China Xiaolei Li, University of Pennsylvania, United States Updates Copyright 2024 Zheng, Liu, Sun and Meng

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The reactivity of this protocol is unique because of the selectivity of the oxidized furan to first add a single thiol followed by the addition of a single amine to generate a chromophoric thio- N -pyrrole heterocycle as the only product under mild conditions and without any catalysts