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Importantly, Gi-F exhibits substantial inhibition of GPX4 activity by assembly enhanced binding ( AEB ) effect, augmenting the oxidative stress of ferriporphyrin-based Fenton reaction, ultimately enabling antitumor properties in multiple tumor models

A., Nalepa, G., Yang, F

Wild type cells had the highest MG than any of the complemented mutant cells (Fig

doi: 10.3389/fimmu.2022.986847 Received 05 July 2022 Accepted 08 September 2022 Published 23 September 2022 Volume 13 - 2022 Edited by Keiji Hirota, Kyoto University, Japan Reviewed by Michihito Kono, Hokkaido University, Japan

Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimers disease