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Fachim HA, Srisawat U, Dalton CF, Reynolds GP

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In ovalbumin (OVA)-induced asthma models, airway inflammation accompanies downregulated endogenous H 2 S generation, while exogenous H 2 S donor supplementation significantly inhibits airway hyperresponsiveness, reduces inflammatory cell infiltration, decreases Th2-type cytokine (IL-4, IL-5, IL-13) expression, and ameliorates airway remodeling (154)