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In the absence of gallbladder alterations, histological analysis of regenerating livers did not reveal abnormalities or signs of accelerated inflammatory reaction in Gstp1/2 / mice (Figure 2)

In view of the finding that oral administration of a synthetic free radical scavenger, MCI-186, can alleviate some symptoms of TS in a mammalian model of the disease, reduction of oxidative stress might prove to be effective in the treatment of TS (Watanabe et al., 2008)

These results suggest that CTCF phosphorylation promotes SATB1 transcription, which is consistent with our RT-qPCR data

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