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doi: 10.1371/journal.pone.0208806

It has been proposed that epithelial and mesenchymal cells survival relies on the signaling provided by integrins attached to a rigid surface and that culturing them in 3D gels leads to cell death by preventing attachment to a rigid surface [26]

studied preventive and curative effects of mangafodipir, a chelate of Mn and ligand fodipir (a vitamin B6 derivative), where Mn is an MRI contrast and vitamin B6 is known for its neuroprotective activity in cancer patients with PIPN (grade 2)

This significant concentration gradient influences the directionality of the adenine nucleotide translocator, preventing it from importing ATP from the cytosol 236

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