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Conclusions: Despite an adequate vitamin status, the supplementation of 1500 mg of L-methionine daily significantly increases homocysteine plasma concentrations by an average of 2.0 mol/l in patients and in control subjects

Cell lysates were analyzed for luciferase activity using the Dual-Luciferase Reporter Assay System (Promega)

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The dose is far higher than what food or pills can deliver

The negative effects of mercury depend mostly on its speciation because different forms of mercury have different levels of bioaccessibility, bioavailability, and toxicokinetics