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Listopad J, Asadullah K, Sievers C, Ritter T, Meisel C, Sabat R, et al

doi: 10.3390/stresses2030019

Despite having an up-regulated basal antioxidant response, STIM1-deficient mouse embryonic fibroblasts experience an imbalance of ROS production and detoxification upon addition of exogenous oxidants (101)

The result is decarboxylation in the first active site and activation of the coenzyme in the second site, which then closes

Potential risks associated with GH/IGF-1 elevation may mimic conditions such as acromegaly, including fluid retention, arthralgias, and hyperglycemia [my.clevelandclinic.org]
