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The data set was analysed using the DAVID, ingenuity pathway analysis (IPA) and GSEA for pathway identification

Greco R, Demartini C, Zanaboni AM, Tumelero E, Persico A, Candeloro E, et al

The payloads for phase III ADCs include three classes of tubulin inhibitors (nine auristatins, one maytansinoid, and one SC209), one class of DNA-damaging agent (one seco-DUBAs), three classes of TOP1 inhibitors (four DXd, one P1003, one SHR9265, one SN-38, one KL610023, one adizutecan, and one exatecan), and a pseudomonas exotoxin (ETA-252608) (Table 2)

three or more susceptibility factors were recognized in 70 % of patients [50]

N -acetylcysteine reverses existing cognitive impairment and increased oxidative stress in glutamate transporter type 3 deficient mice