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Immunofluorescence results showed a significant increase in FOXO4 and p53bp1 foci within the nucleus of senescent cells compared to those in dividing cells (Figure

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Even though similar cellular mechanisms occur also after haematopoietic stem cell transplantation (HSCT) in a process called graft-versus-host disease (GVHD) the role of macrophages in GVHD is still far from being understood [255]

The Phase 2 TRIUMPH trial for Retatrutide enrolled 338 participants with obesity or overweight with comorbidities

Many drugs used to treat obesity in the past have been discontinued because of their potential to be abused and their toxicities [20-27] (Table 1 )