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This is a crucial distinction
At this point, GPX1 surprisingly appears to enhance the initial inflammatory response by initiating the production of pro-inflammatory cytokines to enhance the LPS-induced inflammatory response (Lubos et al., 2010)
No matter how high the drug concentration goes, a point will be reached beyond which no further increment in response is achieved
The critical qualifier: supplementation only produces this effect when B12 deficiency is actually present and was genuinely causing the greying
Oldham JM, Ma SF, Martinez FJ, et al
