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At the moment that the GH dose was decreased or increased the GH-deficient patients in the present study were already treated with GH for more than 1 year (and IGF-1 levels being between 1 and 1 SDS for at least 6 months)

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Pike, L.S., et al., Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells

Transcriptional profiling of rodent OLs with ageing suggests increased engagement of pathways related to antigen presentation, phagocytosis, and interferon signaling 96,97