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A closer look at the findings reveals a more nuanced picture: Total cancers saw a decreased risk of 24% The risk of colon cancer was reduced by 37% There was a 35% decrease in the risk of diabetes Urinary tract infections (UTIs) were reduced by 60% The risk of osteoporosis dropped by 36% Furthermore, a pooled analysis of 30 trials involving 26,708 participants showed a 40% decrease in mortality when estrogen was started before the age of 63, with no significant difference observed when started later