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The methyltransferase complex includes METTL5, tRNA methyltransferase activator subunit 11-2 (TRMT112), Cbl proto-oncogene like 1 (CBLL1), zinc finger protein 217 (ZFP217), RNA binding motif protein 15 (RBM15), RBM15B, and vir-like m6A methyltransferases 59,60

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Inhibition of COX-2 expression and arachidonic acid (AA) metabolism further constrains chronic inflammatory signalling, collectively mitigating inflammageing and supporting immune equilibrium [36,38,199]
