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Kishi Y, Kopetz S , Chun YS, Palavecino M, Abdalla EK, Vauthey JN
Brnnick et al., 2022)
This is curious because of the general assumption that nuclear IGF-1R cannot be accessed by antibodies - crossing the membrane is challenging and import to the nucleus of an antibody bound to IGF-1R is unlikely because of the size of the complex
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