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doi: 10.1016/j.tibs.2013.01.004 67 JiangZ.LinJ.DongH.ZhengX.MarjaniS

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Cha MK, Yun CH, Kim IH

2 Redox biology and endocrine dysregulation in PCOS 2.1 OS pathways in PCOS: sources of ROS and antioxidant defense impairment Emerging evidence identifies PCOS as a disorder of redox dyshomeostasis, contributing to its complex reproductive, endocrine, and metabolic manifestations ( Among endogenous sources, mitochondrial electron transport chain (ETC) inefficiency stands out as a dominant ROS generator in PCOS (31)

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