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APAP overdose is the most common cause of acute liver failure in the US, with around 30,000 patients admitted to hospitals every year, accounting for about 48% of acute liver failure diagnoses [7,8]

Furthermore, this excess serotonin could eventually lead to dysregulation of its production (435)

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MIA models in rodents have shown that a maternal infection may lead to immunological changes that mobilize microglia, thus predisposing offspring to psychosis-like symptoms [49,57]