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Hydroxocobalamin: Often used in injectable B12 formulations, hydroxocobalamin has a longer duration of action than cyanocobalamin

These are a phenomenally bad idea and unfortunately theyre largely dispensed by people with zero medical training and even less knowledge of how the human body works

Systemic side effects may occur in some individuals

In the Sibutramine Cardiovascular Outcomes (SCOUT) trial, the drug was shown to be associated with increased risk of major adverse cardiovascular events (a composite of non-fatal heart attack, non-fatal stroke, resuscitation after cardiac arrest, and cardiovascular death) in obese patients, as compared to placebo [29]