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Description
Free Rad Biol Med 2002
It neutralizes reactive oxygen species (free radicals) and helps protect cells from oxidative stress, which can damage DNA, proteins, and cellular membranes
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In addition, specific amino acid deficiency or the immunosuppressive effect of certain amino acid metabolism can damage the function of immune cells, including effector T cells, in the tumor microenvironment
Interestingly, attack by acetic acid takes place with preference at the epoxide carbon, which is most distal to the double bond (C-9 in the 9(10)-epoxides and C-13 in the 12(13)-epoxides)
