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Notably, human genome-wide association study (GWAS) data have shown that single-nucleotide polymorphisms in the vicinity of the TGFBI gene are associated with type 1 diabetes risk, and TGFBI has been shown to promote islet survival, function and regeneration in mice [43]

Individuals recovering from major illness, trauma, or abdominal surgery represent key target groups, with certain clinical settings showing reduced complication risks and improved tissue recovery

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The Japanese Association for Molecular Target Therapy of Cancer, 2014
