oral melanotic macule images Macule: Symptoms and Treatment Pigmented Lesions of the Oral
Description
The approaches are designed to recognize and bind to specific mtDNA sequences, induce a double-strand break, and initiate targeted degradation of the mutant mtDNA in a heteroplasmic population

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Diehl, P

Proc Natl Acad Sci U S A 116(9):3530-5 2019 PMC6397593 Hogan MF, Ziemann M, K NH, Rodriguez H, Kaspi A, Esser N, Templin AT, El-Osta A, Kahn SE

more usually these largest forms are known as large or giant congenital melanocytic nevus