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Regulation of Nrf2-mediated phase II detoxification and anti-oxidant genes

LA (100 or 200 mg/kg) can act by preventing the activation of the SIRT1/liver kinase B1 (LKB1) AMPK pathway and the translocation of SREBP1 into the nucleus and FOXO1) into the cytoplasm
Siegel R, Miller K, Wagle N, Jemal A

lactate dehydrogenase catalyzed reaction d
