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Studies in mice, rats, rabbits, and dogs found no severe toxic effects across a wide dose range from 6mcg/kg to 20mg/kg

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The most common time to see side effects like these are when you initially start the medication or when you are increasing the dose

Hannibal L, Lysne V, Bjrke-Monsen A, Behringer S, Grnert S, Spiekerkoetter U, Jacobsen D, Blom H

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