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Furthermore, other antioxidant agents, such as vitamin E (73), thioredoxin (74), and aldehydeketone reductase family 1, also play certain roles in ferroptosis (75)

Ablation of all NR4A members prevents terminal exhaustion of CD8 T cells, resulting in the replacement of exhausted cells with effector-like T cells characterized by low PD-1 and Tim-3 expression [44]

1 The open-label phase 3 trial, which included 809 participants with a mean baseline weight of 114.2 kg, showed that tirzepatide led to a slightly higher weight loss of 25.5% under the same efficacy estimand

[DOI] [PMC free article] [PubMed] [Google Scholar] 52.Balachandran P., Pugh N.D., Ma G., Pasco D.S

10.1126/science.1185988 119 NystoriakM
