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In line with this observation, cholesterol-enriched mitochondria from the human hepatocellular cell line HepG2 displayed an impaired initial rate of GSH uptake at different GSH concentrations, an effect that was reversed on fluidization of mitochondria with A 2 C, whereas the uptake of ADP through the adenine nucleotide translocator was unaffected (85)

ISSN 1136-4890

The ED 50 for this effect is 0.38-2.174 ng/mL

Khan M, et al

He, X.-K., Yuan, Z.-X., Wu, X.-J., Xu, C.-Q
