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In the study, the frequency and duration of attacks, the severity of headaches, and monthly medication consumption were significantly reduced in migraine patients compared to the placebo group

This allows more oxygen to dissolve in the bloodstream, reaching tissues that may not be getting enough oxygen under regular circumstances

doi:10.1001/jama.2009.1622 [10] Arakawa Y, Watanabe M, Inoue N, et al

This review has shown that IONP-challenged macrophages initiate a series of processes that trigger an activation towards an antimicrobial M1 phenotype (inflammatory response), capable of eliminating Leishmania