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NAC supports healthy glutathione levels, helps with detox pathways in the liver, and supports overall respiratory well-being

thus, understanding the mechanisms behind this resistance can significantly improve treatment efficacy and patient outcomes [177]

In particular embodiments, the upregulated proteins are one or more selected from antigen presenting molecules (e.g., MHC class I and II), cytokine receptors (e.g., IL-6 receptors, IL-10 receptors, IL-12 receptors, TNF- receptor, TNF- receptor, IFN- receptor, IFN- receptor, IFN-), chemokine receptors (e.g., chemokine receptor 7), costimulatory molecules (e.g., CD3, CD28, CD27, CD30, CD40, CD69, CD80/B7-1, CD86/B7-2, CD134/OX-40, OX-40L, CD137/4-1BB, 4-1BBL, CD278/ICOS, B7-H3, B7h/B7RP-1, LIGHT etc.), HLA-DR and T cell maturation regulatory proteins (e.g.,indoleamine2,3-dioxygenase)

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