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1 Dehydration = Dullness Alcohol is a diuretic it pulls water out of your system, including your skin

Consistent with decreased fasting glucose levels and improved insulin tolerance observed under chow, and to a lesser extent under HFD conditions (Figure 1, H and I, and Figure 2, J and L), GSH depletion significantly downregulated gluconeogenic enzymes G6pc and Pck1 in chow-fed mice, with no substantial change under HFD (Figure 3, A and B)

This theory is that free radicals, as by-products of mitochondrial oxidative metabolism, cause cumulative cellular damage that results in overall loss of organismal fitness over time

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