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In essence, managing neurological disorders needs a holistic approach to tackle their multifaceted challenges, recognizing their substantial prevalence and impact on society

All data were analyzed using Microsoft Excel

The uptake and metabolism process of OHP in glia cells and neurons should be considered

As concern the first, the cathepsin-mediated cell death, our data are in line with those provided by other authors, demonstrating that inhibitors of autophagy, i.e., CQ and the phytochemical thymoquinone, could mediate lysosome permeability, resulting in leakage of cathepsin B into the cytosol where it can act as mediator of cell death 47

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