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According to the IELT, the subjects were classified into 3 groups

Melatonin Dogs under 25 lbs 1.5 mg once or twice daily Medium to large dogs 3 mg once or twice daily Dogs over 100 lbs 6 mg once or twice daily Lignans (dosing recommended by University of Tennessee) Dogs under 25 lbs 10 mg daily Medium to large dogs 20 to 30 mg daily Dogs over 100 lbs 40 mg daily

Convenient Capsule FormEasy-to-swallow capsules make daily supplementation simple and hassle-free

Ethics approval The Medical Ethical Committee of the University Medical Center Groningen stated that the Medical Research Involving Human Subjects Act was not applicable and that official study review and approval by the Medical Ethical Committee were not required (METc 2019/119)