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But animal studies extending up to 6 months show no organ toxicity or adverse histological changes (Sikiric et al., Toxicology and Applied Pharmacology, 2019)

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Once the peptide is fully in solution, add bacteriostatic water to reach the desired final concentration

Neutrophils are thought to promote cuprizone demyelination as knocking out the neutrophil chemokine receptor, CXCR2, in mice prevents demyelination at week 6 of cuprizone treatment