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J Cell Commun Signal 11: 39-48 (2017)

Clinical presentation includes the triad of cirrhosis Cirrhosis Cirrhosis is a late stage of hepatic parenchymal necrosis and scarring (fibrosis) most commonly due to hepatitis C infection and alcoholic liver disease

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Lithium protects against oxidative stress-mediated cell death in -synuclein-overexpressing in vitro and in vivo models of parkinsons disease

Intervention study While the studies cited above are largely consistent with the existence of a high-folatelow-vitamin B-12 interaction affecting both tHcy and MMA metabolism, data are limited on the effect of high-dose folic acid supplements on these 2 biomarkers in vitamin B-12deficient individuals