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These are just typical clinical ranges
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When combined, the SNAC allows oral cyanocobalamin to bypass the usual B12 absorption pathways , which are often impaired in people with B12 deficiency
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The model suggests an exchange with glutamate, but no mitochondrial GABA/glutamate exchanger is known in mammalian cells, although an exchanger has been demonstrated in plants (Michaeli et al., 2011), and the cell membrane of prokaryotes (which have no mitochondria) express a glutamateGABA exchanger, GadC (Ma et al., 2012)
