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doi:10.1021/acs.chemrev.3c00705 282

It may take your doctor several attempts to get the dosing and medication right before you start feeling better

[DOI] [Google Scholar] 181.Ferreira H.P., Parra D.F., Lugao A.B

It causes an immediate release of almost all the granules (containing serotonin, histamine, chemokines, cytokines, enzymes, heparin, and prostaglandins), which trigger itching, swelling, mucous, and anaphylaxis.[ref] A delayed response by mast cells comes from the formation of other mediators, such as prostaglandin D2

Theres much about the etiology of EIPH that we still dont know, says Dr
